In order to assess the health of blood vessels in the retina and choroid, a yellow dye called fluorescein is injected into a vein in the arm, and pictures are taken of the retina. These images are helpful in determining if the retinal vessels are healthy or damaged from a variety of retinal conditions such as diabetic retinopathy, macular degeneration, retinal vein occlusion, and others. Fluorescein dye can sometimes cause brief nausea, usually turns the urine and skin yellow-orange for several hours, and can rarely cause severe anaphylactic reactions.